5A54
DYRK1A IN COMPLEX WITH NITRO BENZOTHIAZOLE FRAGMENT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A | polymer | 368 | 42654.0 | 4 | UniProt (Q13627) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | DUAL SPECIFICITY YAK1-RELATED KINASE, HP86, PROTEIN KINASE MINIBRAIN HOMOLOG, MNBH, HMNB |
| 2 | E, F, G, H (A, B, C, D) | N-(6-nitro-1,3-benzothiazol-2-yl)ethanamide | non-polymer | 237.2 | 4 | Chemie (5PW) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 126 - 490 (UniProt: Q13627)
| PDB | External Database | Details |
|---|---|---|
| Gly 123 | - | expression tag |
| Ala 124 | - | expression tag |
| Ser 125 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 170616.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 948.9 | |
| All* | Total formula weight | 171564.9 |
