5A4T
DYRK1A IN COMPLEX WITH NITRILE BENZOTHIAZOLE FRAGMENT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION- REGULATED KINASE 1A | polymer | 368 | 42654.0 | 4 | UniProt (Q13627) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | DUAL SPECIFICITY YAK1-RELATED KINASE, HP86, PROTEIN KINASE MINIBRAIN HOMOLOG, MNBH, HMNB, DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A |
| 2 | A, B, C, D | N-(6-CYANO-3H-1,3-BENZOTHIAZOL-2-YLIDENE)ETHANAMIDE | non-polymer | 217.2 | 4 | Chemie (AJG) | |||
| 3 | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 126 - 490 (UniProt: Q13627)
| PDB | External Database | Details |
|---|---|---|
| Gly 123 | - | expression tag |
| Ala 124 | - | expression tag |
| Ser 125 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 170616.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 869.0 | |
| All* | Total formula weight | 171485.0 |
