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4ZYR

Crystal structure of E. coli Lactose permease G46W/G262W bound to p-nitrophenyl alpha-D-galactopyranoside (alpha-NPG)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Lactose permeasepolymer41746789.22UniProt (P02920)
Pfam (PF01306)
Escherichia coli (strain K12)Lactose-proton symport
2C, E
(A, B)
4-nitrophenyl alpha-D-galactopyranosidenon-polymer301.22Chemie (9PG)
3D, F
(A, B)
nonyl beta-D-glucopyranosidenon-polymer306.42Chemie (BNG)
Sequence modifications
A, B: 1 - 417 (UniProt: P02920)
PDBExternal DatabaseDetails
Trp 46Gly 46engineered mutation
Trp 262Gly 262engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight93578.4
Non-Polymers*Number of molecules4
Total formula weight1215.3
All*Total formula weight94793.7
*Water molecules are not included.

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PDB entries from 2025-07-30

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