4ZYR
Crystal structure of E. coli Lactose permease G46W/G262W bound to p-nitrophenyl alpha-D-galactopyranoside (alpha-NPG)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Lactose permease | polymer | 417 | 46789.2 | 2 | UniProt (P02920) Pfam (PF01306) | Escherichia coli (strain K12) | Lactose-proton symport |
| 2 | C, E (A, B) | 4-nitrophenyl alpha-D-galactopyranoside | non-polymer | 301.2 | 2 | Chemie (9PG) | |||
| 3 | D, F (A, B) | nonyl beta-D-glucopyranoside | non-polymer | 306.4 | 2 | Chemie (BNG) |
Sequence modifications
A, B: 1 - 417 (UniProt: P02920)
| PDB | External Database | Details |
|---|---|---|
| Trp 46 | Gly 46 | engineered mutation |
| Trp 262 | Gly 262 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 93578.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1215.3 | |
| All* | Total formula weight | 94793.7 |
