4ZWP
Crystal structure of organophosphate anhydrolase/prolidase mutant Y212F
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | OPAA organophosphate prolidase anhydrolase | polymer | 440 | 50389.6 | 2 | UniProt (Q44238) Pfam (PF21216) Pfam (PF00557) In PDB | Alteromonas sp. | X-Pro dipeptidase,DFPase,Imidodipeptidase,Organophosphorus acid anhydrolase 2,OPAA-2,Paraoxon hydrolase,Phosphotriesterase,Proline dipeptidase,Prolidase |
| 2 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 7 | Chemie (MN) | |||
| 3 | A | BARIUM ION | non-polymer | 137.3 | 3 | Chemie (BA) | |||
| 4 | A, B | N,N'-bis(1-methylethyl)phosphorodiamidic acid | non-polymer | 180.2 | 2 | Chemie (M44) | |||
| 5 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 377 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 437 (UniProt: Q44238)
| PDB | External Database | Details |
|---|---|---|
| Thr 210 | Asn 210 | variant |
| Pro 211 | Ala 211 | variant |
| Phe 212 | Tyr 212 | engineered mutation |
| Asn 314 | Asp 314 | variant |
| Glu 438 | - | expression tag |
| Leu 439 | - | expression tag |
| Asp 440 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 100779.2 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1249.0 | |
| All* | Total formula weight | 102028.2 |
