4ZVM
Oxidized quinone reductase 2 in complex with doxorubicin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ribosyldihydronicotinamide dehydrogenase [quinone] | polymer | 230 | 25849.3 | 2 | UniProt (P16083) Pfam (PF02525) | Homo sapiens (Human) | NRH dehydrogenase [quinone] 2,NRH:quinone oxidoreductase 2,Quinone reductase 2,QR2 |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 4 | E, H (A, B) | DOXORUBICIN | non-polymer | 543.5 | 2 | Chemie (DM2) PubChem (1691) PubChem (32875) PubChem (41867) PubChem (83979) PubChem (23637978) PubChem (151537) PubChem (153517) PubChem (71199382) PubChem (17572077) PubChem (24871487) PubChem (44119991) PubChem (44307587) PubChem (44784745) PubChem (44286103) PubChem (51340272) PubChem (45039140) PubChem (45039115) PubChem (53298795) PubChem (53298798) PubChem (53487962) PubChem (56841075) PubChem (57156654) PubChem (3085300) PubChem (3246521) PubChem (57654443) PubChem (57676190) PubChem (57684283) PubChem (58166317) PubChem (58641042) PubChem (58918741) PubChem (59360012) PubChem (59392534) PubChem (66509033) PubChem (66687678) PubChem (58599010) PubChem (58648994) PubChem (67476623) PubChem (71113872) PubChem (68031993) PubChem (68652619) PubChem (69505664) PubChem (66728492) PubChem (70791143) PubChem (68247330) PubChem (5706446) PubChem (31703) PubChem (6604382) PubChem (6711224) PubChem (6713707) PubChem (89728269) PubChem (89728271) PubChem (89802959) PubChem (89848182) PubChem (89955946) PubChem (89970500) PubChem (91091768) PubChem (92209262) PubChem (92209263) PubChem (92402748) PubChem (11295712) PubChem (92849511) PubChem (92849512) PubChem (3246615) PubChem (155908452) PubChem (15558386) PubChem (15558389) PubChem (15558390) PubChem (15558391) PubChem (15558395) PubChem (15558402) PubChem (15558405) PubChem (15558406) PubChem (92249481) PubChem (100967544) PubChem (118547678) PubChem (121459604) PubChem (6916127) PubChem (124583220) PubChem (124535760) PubChem (102361707) PubChem (129010031) PubChem (132241129) PubChem (118459001) PubChem (11713633) PubChem (135228351) PubChem (122172883) PubChem (124289489) PubChem (124535759) PubChem (124785323) PubChem (129010226) PubChem (129069944) PubChem (130250494) PubChem (15558384) PubChem (15558393) PubChem (15558400) PubChem (15558397) PubChem (15558396) PubChem (15558404) PubChem (15940176) PubChem (155096397) PubChem (135219625) PubChem (162148270) PubChem (162981689) PubChem (138392495) PubChem (145978921) PubChem (146981399) PubChem (153419025) PubChem (157179210) PubChem (145082776) PubChem (162981688) PubChem (173942463) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 230 (UniProt: P16083)
| PDB | External Database | Details |
|---|---|---|
| Phe 46 | Leu 47 | see remark 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51698.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2789.0 | |
| All* | Total formula weight | 54487.6 |
