4ZUH

Complex structure of PEDV 3CLpro mutant (C144A) with a peptide substrate.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	PEDV 3C-Like protease	polymer	305	33263.6	2	UniProt (K4L9I6) Pfam (PF05409) UniProt (by SIFTS) (R4JK63) In PDB	Porcine epidemic diarrhea virus
2	C	peptide substrate SAVLQSGF	polymer	11	1195.4	1	UniProt (by SIFTS) (P0C6X7) In PDB	synthetic construct
3		water	water		18.0	267	Chemie (HOH)

Sequence modifications

A, B: 1 - 299 (UniProt: K4L9I6)

PDB	External Database	Details
Ala 144	Cys 3141	engineered mutation
His 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	67722.5
All*	Total formula weight	67722.5

*Water molecules are not included.