4ZUH
Complex structure of PEDV 3CLpro mutant (C144A) with a peptide substrate.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PEDV 3C-Like protease | polymer | 305 | 33263.6 | 2 | UniProt (K4L9I6) Pfam (PF05409) UniProt (by SIFTS) (R4JK63) | Porcine epidemic diarrhea virus | |
| 2 | C (C) | peptide substrate SAVLQSGF | polymer | 11 | 1195.4 | 1 | UniProt (by SIFTS) (P0C6X7) | synthetic construct | |
| 3 | D, E (A, B) | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 299 (UniProt: K4L9I6)
| PDB | External Database | Details |
|---|---|---|
| Ala 144 | Cys 3141 | engineered mutation |
| His 300 | - | expression tag |
| His 301 | - | expression tag |
| His 302 | - | expression tag |
| His 303 | - | expression tag |
| His 304 | - | expression tag |
| His 305 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 67722.5 | |
| All* | Total formula weight | 67722.5 |
