4ZU7
X-ray structure if the QdtA 3,4-ketoisomerase from Thermoanaerobacterium thermosaccharolyticum, double mutant Y17R/R97H, in complex with TDP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | QdtA | polymer | 144 | 17140.8 | 8 | UniProt (Q6TFC5) Pfam (PF05523) In PDB | Thermoanaerobacterium thermosaccharolyticum | |
2 | A, B, C, D, E... | THYMIDINE-5'-DIPHOSPHATE | non-polymer | 402.2 | 8 | Chemie (TYD) | |||
3 | D | (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol | non-polymer | 368.5 | 1 | Chemie (PXN) | |||
4 | water | water | 18.0 | 179 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 136 (UniProt: Q6TFC5)
PDB | External Database | Details |
---|---|---|
Arg 17 | Tyr 17 | engineered mutation |
Ser 52 | Ala 52 | SEE REMARK 999 |
Leu 94 | Phe 94 | SEE REMARK 999 |
Val 95 | Leu 95 | SEE REMARK 999 |
His 97 | Arg 97 | engineered mutation |
Tyr 116 | Cys 116 | SEE REMARK 999 |
Leu 137 | - | expression tag |
Glu 138 | - | expression tag |
His 139 | - | expression tag |
His 140 | - | expression tag |
His 141 | - | expression tag |
His 142 | - | expression tag |
His 143 | - | expression tag |
His 144 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 137126.3 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 3586.0 | |
All* | Total formula weight | 140712.3 |