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4ZTM

Irak4-inhibitor co-structure

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Interleukin-1 receptor-associated kinase 4polymer30133956.24UniProt (Q9NWZ3)
Pfam (PF07714)
Homo sapiens (Human)IRAK-4,Renal carcinoma antigen NY-REN-64
2E, F, G, H
(A, B, C, D)
5-(1,3-benzothiazol-2-yl)-2-(cyclopropylamino)-6-{[(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]amino}pyrimidin-4(3H)-onenon-polymer429.54Chemie (4S2)
3I, J, K, L
(A, B, C, D)
waterwater18.0105Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight135824.8
Non-Polymers*Number of molecules4
Total formula weight1718.0
All*Total formula weight137542.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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