4ZT0
Crystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | CRISPR-associated endonuclease Cas9 | polymer | 1369 | 159804.6 | 2 | UniProt (A0A0C6FZC2) Pfam (PF16593) Pfam (PF16592) Pfam (PF13395) Pfam (PF22702) Pfam (PF16595) UniProt (by SIFTS) (Q99ZW2) In PDB | Streptococcus pyogenes | Csn1 protein, Cas9, CRISPR-Cas9 |
2 | B, D | single-guide RNA | polymer | 85 | 27501.4 | 2 | Streptococcus pyogenes |
Sequence modifications
A, C: 2 - 1368 (UniProt: A0A0C6FZC2)
PDB | External Database | Details |
---|---|---|
Ser 0 | - | expression tag |
Mse 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 374612.0 | |
All* | Total formula weight | 374612.0 |