4ZS3
Structural complex of 5-aminofluorescein bound to the FTO protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-ketoglutarate-dependent dioxygenase FTO | polymer | 478 | 54934.0 | 1 | UniProt (Q9C0B1) Pfam (PF12933) Pfam (PF12934) | Homo sapiens (Human) | Fat mass and obesity-associated protein |
| 2 | B (A) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) | |||
| 3 | C (A) | 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid | non-polymer | 347.3 | 1 | Chemie (A4F) | |||
| 4 | D (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 5 | E (A) | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
A: 32 - 505 (UniProt: Q9C0B1)
| PDB | External Database | Details |
|---|---|---|
| Gly 28 | - | expression tag |
| Ser 29 | - | expression tag |
| His 30 | - | expression tag |
| Met 31 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 54934.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 548.4 | |
| All* | Total formula weight | 55482.3 |
