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4ZQC

Tryptophan Synthase from Salmonella typhimurium in complex with two molecules of N-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6F) inhibitor in the alpha-site and a single F6F molecule in the beta-site at 1.54 Angstrom resolution.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tryptophan synthase alpha chainpolymer26828698.81UniProt (P00929)
Pfam (PF00290)
Salmonella enterica subsp. enterica serovar Typhimurium
2B
(B)
Tryptophan synthase beta chainpolymer39742918.91UniProt (P0A2K1)
Pfam (PF00291)
Salmonella enterica subsp. enterica serovar Typhimurium
3C, D, I
(A, B)
2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL DIHYDROGEN PHOSPHATEnon-polymer329.23Chemie (F6F)
4E, F, G, K, L...
(A, B)
DIMETHYL SULFOXIDEnon-polymer78.112Chemie (DMS)
5H
(B)
PYRIDOXAL-5'-PHOSPHATEnon-polymer247.11Chemie (PLP)
6J
(B)
SODIUM IONnon-polymer23.01Chemie (NA)
7T, U
(A, B)
waterwater18.0831Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight71617.7
Non-Polymers*Number of molecules17
Total formula weight2195.2
All*Total formula weight73812.9
*Water molecules are not included.

237423

PDB entries from 2025-06-11

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