4ZP0
Crystal structure of E. coli multidrug transporter MdfA in complex with deoxycholate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Multidrug transporter MdfA | polymer | 392 | 42461.6 | 1 | UniProt (P0AEY8) Pfam (PF07690) | Escherichia coli (strain K12) | Chloramphenicol resistance pump Cmr |
| 2 | B (A) | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID | non-polymer | 392.6 | 1 | Chemie (DXC) | |||
| 3 | C, D (A) | LAURYL DIMETHYLAMINE-N-OXIDE | non-polymer | 229.4 | 2 | Chemie (LDA) | |||
| 4 | E (A) | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A: 9 - 400 (UniProt: P0AEY8)
| PDB | External Database | Details |
|---|---|---|
| Arg 131 | Gln 131 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42461.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 851.4 | |
| All* | Total formula weight | 43313.0 |
