4ZJI
PAK1 in complex with 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Serine/threonine-protein kinase PAK 1 | polymer | 299 | 33413.4 | 4 | UniProt (Q13153) Pfam (PF00069) | Homo sapiens (Human) | Alpha-PAK,p21-activated kinase 1,PAK-1,p65-PAK |
| 2 | E, F, G, I (A, B, C, D) | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | non-polymer | 372.9 | 4 | Chemie (4OQ) | |||
| 3 | H, J (C, D) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 795 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 249 - 545 (UniProt: Q13153)
| PDB | External Database | Details |
|---|---|---|
| Gly 247 | - | expression tag |
| Pro 248 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 133653.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1540.1 | |
| All* | Total formula weight | 135193.7 |
