4ZHC
Siderocalin-mediated recognition and cellular uptake of actinides
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Neutrophil gelatinase-associated lipocalin | polymer | 180 | 20700.6 | 3 | UniProt (P80188) Pfam (PF00061) | Homo sapiens (Human) | NGAL,25 kDa alpha-2-microglobulin-related subunit of MMP-9,Lipocalin-2,Oncogene 24p3,Siderocalin LCN2,p25 |
| 2 | D, G, I (A, B, C) | THORIUM ION | non-polymer | 232.0 | 3 | Chemie (TH) | |||
| 3 | E, H, J (A, B, C) | N-{2-[bis(2-{[(2,3-dihydroxyphenyl)carbonyl]amino}ethyl)amino]ethyl}-1-hydroxy-6-oxo-1,6-dihydropyridine-2-carboxamide | non-polymer | 555.5 | 3 | Chemie (TC2) | |||
| 4 | F, M (A, C) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 5 | K, L (C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | N, O, P (A, B, C) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 178 (UniProt: P80188)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ser 87 | Cys 107 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 62101.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2672.9 | |
| All* | Total formula weight | 64774.6 |
