4ZH4
Crystal structure of Escherichia coli RNA polymerase in complex with CBRP18
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, G, H (A, B, G, H) | DNA-directed RNA polymerase subunit alpha | polymer | 335 | 37387.5 | 4 | UniProt (P0A7Z4) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) | Escherichia coli | RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha |
| 2 | C, I (C, I) | DNA-directed RNA polymerase subunit beta | polymer | 1342 | 150820.9 | 2 | UniProt (P0A8V2) Pfam (PF04560) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) | Escherichia coli (strain K12) | RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta |
| 3 | D, J (D, J) | DNA-directed RNA polymerase subunit beta' | polymer | 1407 | 155366.8 | 2 | UniProt (P0A8T7) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) | Escherichia coli (strain K12) | RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta' |
| 4 | E, K (E, K) | DNA-directed RNA polymerase subunit omega | polymer | 91 | 10249.5 | 2 | UniProt (P0A800) Pfam (PF01192) | Escherichia coli (strain K12) | RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega |
| 5 | F, L (F, L) | RNA polymerase sigma factor RpoD | polymer | 613 | 70352.2 | 2 | UniProt (P00579) Pfam (PF03979) Pfam (PF00140) Pfam (PF04546) Pfam (PF04542) Pfam (PF04539) Pfam (PF04545) | Escherichia coli (strain K12) | Sigma-70 |
| 6 | M, Q (C, I) | 5-(4-fluorophenyl)-4-[4-fluoro-3-(trifluoromethyl)phenyl]-1H-pyrazole | non-polymer | 324.2 | 2 | Chemie (4OE) | |||
| 7 | N, R (D, J) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 8 | O, P, S, T (D, J) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
A, B, G, H: 2 - 329 (UniProt: P0A7Z4)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 923129.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 958.7 | |
| All* | Total formula weight | 924087.8 |
