4ZEW

Crystal structure of PfHAD1 in complex with glucose-6-phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	PfHAD1	polymer	296	33870.6	2	UniProt (Q8IJ74) Pfam (PF08282) In PDB	Plasmodium falciparum (isolate 3D7)
2	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	A	6-O-phosphono-alpha-D-glucopyranose	non-polymer		260.1	1	Chemie (G6P)
4	B	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
5		water	water		18.0	288	Chemie (HOH)

Sequence modifications

A, B: 1 - 288 (UniProt: Q8IJ74)

PDB	External Database	Details
Met -7	-	expression tag
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Ala 27	Asp 27	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67741.3
Non-Polymers*	Number of molecules	4
	Total formula weight	403.7
All*	Total formula weight	68145.0

*Water molecules are not included.