4ZEV
Crystal structure of PfHAD1 in complex with mannose-6-phosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PfHAD1 | polymer | 296 | 33870.6 | 2 | UniProt (Q8IJ74) Pfam (PF08282) | Plasmodium falciparum (isolate 3D7) | |
| 2 | C, E (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D (A) | 6-O-phosphono-alpha-D-mannopyranose | non-polymer | 260.1 | 1 | Chemie (M6P) | |||
| 4 | F (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 364 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 288 (UniProt: Q8IJ74)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | expression tag |
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 27 | Asp 27 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67741.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 403.7 | |
| All* | Total formula weight | 68145.0 |
