4ZEV
Crystal structure of PfHAD1 in complex with mannose-6-phosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PfHAD1 | polymer | 296 | 33870.6 | 2 | UniProt (Q8IJ74) Pfam (PF08282) | Plasmodium falciparum (isolate 3D7) | |
| 2 | C, E (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 3 | D (A) | 6-O-phosphono-alpha-D-mannopyranose | non-polymer | 260.1 | 1 | Chemie (M6P) PubChem (208) PubChem (5958) PubChem (65127) PubChem (439198) PubChem (439284) PubChem (439404) PubChem (439427) PubChem (440100) PubChem (447096) PubChem (449526) PubChem (9817215) PubChem (9859975) PubChem (11499884) PubChem (11536233) PubChem (11651816) PubChem (11651817) PubChem (12314997) PubChem (12315003) PubChem (12598269) PubChem (24802166) PubChem (46936284) PubChem (71048769) PubChem (51351674) PubChem (92043642) PubChem (124302956) PubChem (11701643) PubChem (59660208) PubChem (66804219) PubChem (70828590) PubChem (89530481) PubChem (89533633) PubChem (90087729) PubChem (92144442) PubChem (92331698) PubChem (92331699) PubChem (92450038) PubChem (100983220) PubChem (124303605) PubChem (133556303) PubChem (146542296) PubChem (146681138) PubChem (154560390) PubChem (156616945) PubChem (159734910) PubChem (162938850) PubChem (164575487) PubChem (168360205) PubChem (168365572) PubChem (168366721) PubChem (168367148) PubChem (168367891) PubChem (168368101) PubChem (168369931) PubChem (168374583) PubChem (169436999) PubChem (171380675) PubChem (172641742) PubChem (173866441) | |||
| 4 | F (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) PubChem (1061) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 364 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 288 (UniProt: Q8IJ74)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | expression tag |
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 27 | Asp 27 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67741.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 403.7 | |
| All* | Total formula weight | 68145.0 |
