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4ZC6

Crystal Structure of human GGT1 in complex with Serine Borate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Gamma-glutamyltranspeptidase 1 heavy chainpolymer35338533.71UniProt (P19440)
Pfam (PF01019)
Homo sapiens (Human)GGT 1,Gamma-glutamyltransferase 1,Glutathione hydrolase 1,Leukotriene-C4 hydrolase
2B
(B)
Gamma-glutamyltranspeptidase 1 light chainpolymer18920014.41UniProt (P19440)
Pfam (PF01019)
Homo sapiens (Human)GGT 1,Gamma-glutamyltransferase 1,Glutathione hydrolase 1,Leukotriene-C4 hydrolase
3C, D, E, F, G...
(A, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.26Chemie (NAG)
4H, L
(A, B)
CHLORIDE IONnon-polymer35.52Chemie (CL)
5I
(B)
SODIUM IONnon-polymer23.01Chemie (NA)
6K
(B)
trihydroxy(L-serinato-kappaO~3~)borate(1-)non-polymer165.91Chemie (SEE)
7M, N
(A, B)
waterwater18.0335Chemie (HOH)
Sequence modifications
A: 28 - 380 (UniProt: P19440)
PDBExternal DatabaseDetails
Ala 272Val 272variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight58548.1
Non-Polymers*Number of molecules10
Total formula weight1587.1
All*Total formula weight60135.2
*Water molecules are not included.

239149

数据于2025-07-23公开中

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