4ZBK
Crystal Structure of human GGT1 in complex with GGsTop inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Gamma-glutamyltranspeptidase 1 | polymer | 353 | 38533.7 | 1 | UniProt (P19440) Pfam (PF01019) In PDB | Homo sapiens (Human) | GGT 1,Gamma-glutamyltransferase 1,Glutathione hydrolase 1,Leukotriene-C4 hydrolase |
| 2 | B | Gamma-glutamyltranspeptidase 1 | polymer | 189 | 20014.4 | 1 | UniProt (P19440) Pfam (PF01019) In PDB | Homo sapiens (Human) | GGT 1,Gamma-glutamyltransferase 1,Glutathione hydrolase 1,Leukotriene-C4 hydrolase |
| 3 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 4 | A | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | B | (2S)-2-amino-4-[(S)-hydroxy(methoxy)phosphoryl]butanoic acid | non-polymer | 197.1 | 1 | Chemie (4M8) | |||
| 8 | water | water | 18.0 | 337 | Chemie (HOH) |
Sequence modifications
A: 28 - 380 (UniProt: P19440)
| PDB | External Database | Details |
|---|---|---|
| Ala 272 | Val 272 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58548.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2008.7 | |
| All* | Total formula weight | 60556.8 |
