4Z9V
TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bcl-2-like protein 1,APOPTOSIS REGULATOR BCL-XL | polymer | 153 | 17487.5 | 2 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) | Homo sapiens (Human) | Bcl2-L-1,Apoptosis regulator Bcl-X |
| 2 | C, D, E, F, G... (C, D, E, F, G...) | Translationally-controlled tumor protein | polymer | 21 | 2461.8 | 6 | UniProt (P13693) | Homo sapiens (Human) | TCTP,Fortilin,Histamine-releasing factor,HRF,p23 |
| 3 | I, J (A, B) | BICARBONATE ION | non-polymer | 61.0 | 2 | Chemie (BCT) | |||
| 4 | K, L (F, H) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 57 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 26 (UniProt: Q07817)
A, B: 83 - 208 (UniProt: Q07817)
| PDB | External Database | Details |
|---|---|---|
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 49745.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 168.0 | |
| All* | Total formula weight | 49913.8 |
