4Z8M

Crystal structure of the MAVS-TRAF6 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	TNF receptor-associated factor 6	polymer	169	19778.8	2	UniProt (Q9Y4K3) Pfam (PF21355)	Homo sapiens (Human)	E3 ubiquitin-protein ligase TRAF6,Interleukin-1 signal transducer,RING finger protein 85
2	C, D (C, D)	Peptide from Mitochondrial antiviral-signaling protein	polymer	19	2053.2	2	UniProt (Q7Z434)	Homo sapiens (Human)	MAVS,CARD adapter inducing interferon beta,Cardif,Interferon beta promoter stimulator protein 1,IPS-1,Putative NF-kappa-B-activating protein 031N,Virus-induced-signaling adapter,VISA

Sequence modifications

A, B: 346 - 504 (UniProt: Q9Y4K3)

PDB	External Database	Details
Met 344	-	expression tag
Ala 345	-	expression tag
Leu 505	-	expression tag
Glu 506	-	expression tag
His 507	-	expression tag
His 508	-	expression tag
His 509	-	expression tag
His 510	-	expression tag
His 511	-	expression tag
His 512	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	43663.9
All*	Total formula weight	43663.9

*Water molecules are not included.