4Z7Q
Integrin alphaIIbbeta3 in complex with AGDV-NH2 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Integrin alpha-IIb | polymer | 454 | 49228.6 | 2 | UniProt (P08514) Pfam (PF01839) | Homo sapiens (Human) | GPalpha IIb,GPIIb,Platelet membrane glycoprotein IIb |
| 2 | B, D (B, D) | Integrin beta-3 | polymer | 471 | 51958.8 | 2 | UniProt (P05106) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372) | Homo sapiens (Human) | Platelet membrane glycoprotein IIIa,GPIIIa |
| 3 | E, G (E, H) | Monoclonal antibody 10E5 heavy chain | polymer | 219 | 23612.3 | 2 | Mus musculus | ||
| 4 | F, H (F, L) | Monoclonal antibody 10E5 light chain | polymer | 214 | 23332.7 | 2 | Mus musculus | ||
| 5 | I, J (G, I) | Tetrapeptide AGDV-NH2 | polymer | 5 | 358.4 | 2 | Homo sapiens | ||
| 6 | K (J) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 7 | L, N (K, N) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 8 | M (M) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 9 | AA, BA, CA, DA, O... (C, A) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 10 | FA, GA, HA, NA, S... (C, L, A) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 11 | V (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 12 | JA, KA, MA, W, X... (D, B) | MANGANESE (II) ION | non-polymer | 54.9 | 6 | Chemie (MN) | |||
| 13 | LA, Z (D, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 14 | EA (C) | alpha-D-mannopyranose | non-polymer | 180.2 | 1 | Chemie (MAN) | |||
| 15 | IA (C) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 16 | OA, PA, QA, RA, SA... (A, B, C, D, E...) | water | water | 18.0 | 991 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 296981.6 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2346.2 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 2072.8 | |
| All* | Total formula weight | 301400.5 |
