4Z33
Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Syntenin-1 | polymer | 166 | 18064.8 | 2 | UniProt (O00560) Pfam (PF00595) In PDB | Homo sapiens (Human) | Melanoma differentiation-associated protein 9,MDA-9,Pro-TGF-alpha cytoplasmic domain-interacting protein 18,TACIP18,Scaffold protein Pbp1,Syndecan-binding protein 1 |
2 | C, D | LYS-GLY-GLU-THR-ALA-VAL | polymer | 6 | 604.7 | 2 | UniProt (by SIFTS) (O75084) In PDB | Homo sapiens | |
3 | A, B | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
5 | A | D-MYO-INOSITOL-4,5-BISPHOSPHATE | non-polymer | 340.1 | 1 | Chemie (IP2) | |||
6 | water | water | 18.0 | 163 | Chemie (HOH) |
Sequence modifications
A, B: 111 - 275 (UniProt: O00560)
PDB | External Database | Details |
---|---|---|
Ser 110 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 37338.9 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 760.5 | |
All* | Total formula weight | 38099.4 |