4Z2A
Crystal structure of unglycosylated apo human furin @1.89A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Furin | polymer | 465 | 50505.6 | 1 | UniProt (P09958) Pfam (PF00082) Pfam (PF01483) | Homo sapiens (Human) | Dibasic-processing enzyme,Paired basic amino acid residue-cleaving enzyme,PACE |
| 2 | B, C, D, E (A) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 3 | F, G (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | I (A) | water | water | 18.0 | 408 | Chemie (HOH) |
Sequence modifications
A: 110 - 574 (UniProt: P09958)
| PDB | External Database | Details |
|---|---|---|
| Asp 387 | Asn 387 | engineered mutation |
| Asp 440 | Asn 440 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 50505.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 412.3 | |
| All* | Total formula weight | 50917.9 |
