4Z2A
Crystal structure of unglycosylated apo human furin @1.89A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Furin | polymer | 465 | 50505.6 | 1 | UniProt (P09958) Pfam (PF00082) Pfam (PF01483) In PDB | Homo sapiens (Human) | Dibasic-processing enzyme,Paired basic amino acid residue-cleaving enzyme,PACE |
2 | A | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
3 | A | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
5 | water | water | 18.0 | 408 | Chemie (HOH) |
Sequence modifications
A: 110 - 574 (UniProt: P09958)
PDB | External Database | Details |
---|---|---|
Asp 387 | Asn 387 | engineered mutation |
Asp 440 | Asn 440 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 50505.6 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 412.3 | |
All* | Total formula weight | 50917.9 |