4Z1V
Structure of Factor Inhibiting HIF (FIH) in complex with Fe, NO, and NOG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hypoxia-inducible factor 1-alpha inhibitor | polymer | 352 | 40610.6 | 1 | UniProt (Q9NWT6) Pfam (PF13621) | Homo sapiens (Human) | Factor inhibiting HIF-1,FIH-1,Hypoxia-inducible factor asparagine hydroxylase |
| 2 | B (A) | N-OXALYLGLYCINE | non-polymer | 147.1 | 1 | Chemie (OGA) | |||
| 3 | C (A) | NITRIC OXIDE | non-polymer | 30.0 | 1 | Chemie (NO) | |||
| 4 | D (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | E (A) | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
| 6 | F, G, H, I, J (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 7 | K (A) | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence modifications
A: 1 - 349 (UniProt: Q9NWT6)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40610.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 819.4 | |
| All* | Total formula weight | 41429.9 |
