4YZ5
Crystal Structure of Streptococcus pneumoniae NanC, in complex with 3-Sialyllactose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Putative neuraminidase | polymer | 677 | 75996.8 | 2 | UniProt (Q97Q99) Pfam (PF02973) Pfam (PF02012) Pfam (PF13088) UniProt (by SIFTS) (A0A0H2UQE4) | Streptococcus pneumoniae | |
| 2 | C, D (C, D) | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | branched | 633.6 | 2 | In PDB BIRD (PRD_900025) GlyTouCan (G92323ZH) | 3'-sialyl-alpha-lactose | ||
| 3 | E, K (A, B) | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID | non-polymer | 291.3 | 2 | Chemie (DAN) | |||
| 4 | F, G, H, I, J... (A, B) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 5 | Q, R (A, B) | water | water | 18.0 | 721 | Chemie (HOH) |
Sequence modifications
A, B: 84 - 740 (UniProt: Q97Q99)
| PDB | External Database | Details |
|---|---|---|
| Met 64 | - | initiating methionine |
| Ala 65 | - | expression tag |
| His 66 | - | expression tag |
| His 67 | - | expression tag |
| His 68 | - | expression tag |
| His 69 | - | expression tag |
| His 70 | - | expression tag |
| His 71 | - | expression tag |
| Ser 72 | - | expression tag |
| Ser 73 | - | expression tag |
| Gly 74 | - | expression tag |
| Leu 75 | - | expression tag |
| Glu 76 | - | expression tag |
| Val 77 | - | expression tag |
| Leu 78 | - | expression tag |
| Phe 79 | - | expression tag |
| Gln 80 | - | expression tag |
| Gly 81 | - | expression tag |
| Pro 82 | - | expression tag |
| Asn 83 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 151993.7 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1267.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1543.1 | |
| All* | Total formula weight | 154803.9 |
