4YXL

Crystal structure of Syrian hamster prion protein complexed with POM1 FAB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Major prion protein	polymer	166	18896.0	1	UniProt (P04273) Pfam (PF00377) In PDB	Mesocricetus auratus (Golden hamster)	PrP,PrP27-30,PrP33-35C
2	H	POM1 FAB HEAVY CHAIN	polymer	218	23367.1	1		Mus musculus
3	L	POM1 FAB LIGHT CHAIN	polymer	213	23509.7	1		Mus musculus
4	L	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
5		water	water		18.0	76	Chemie (HOH)

Sequence modifications

A: 90 - 232 (UniProt: P04273)

PDB	External Database	Details
Met 67	-	expression tag
Gly 68	-	expression tag
Ser 69	-	expression tag
Ser 70	-	expression tag
His 71	-	expression tag
His 72	-	expression tag
His 73	-	expression tag
His 74	-	expression tag
His 75	-	expression tag
His 76	-	expression tag
Ser 77	-	expression tag
Ser 78	-	expression tag
Gly 79	-	expression tag
Leu 80	-	expression tag
Val 81	-	expression tag
Pro 82	-	expression tag
Arg 83	-	expression tag
Gly 84	-	expression tag
Ser 85	-	expression tag
His 86	-	expression tag
Met 87	-	expression tag
Leu 88	-	expression tag
Glu 89	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	65772.8
Non-Polymers*	Number of molecules	1
	Total formula weight	23.0
All*	Total formula weight	65795.8

*Water molecules are not included.