4YXK

Crystal structure of Elk prion protein complexed with POM1 FAB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Major prion protein	polymer	135	15931.7	1	UniProt (P67986) Pfam (PF00377)	Cervus elaphus nelsoni (North American elk)	PrP
2	B (H)	POM1 FAB HEAVY CHAIN	polymer	218	23397.1	1		Mus musculus
3	C (L)	POM1 FAB LIGHT CHAIN	polymer	213	23509.7	1		Mus musculus
4	D (L)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
5	E, F, G (A, H, L)	water	water		18.0	73	Chemie (HOH)

Sequence modifications

A: 120 - 227 (UniProt: P67986)

PDB	External Database	Details
Met 93	-	expression tag
Gly 94	-	expression tag
Ser 95	-	expression tag
Ser 96	-	expression tag
His 97	-	expression tag
His 98	-	expression tag
His 99	-	expression tag
His 100	-	expression tag
His 101	-	expression tag
His 102	-	expression tag
Ser 103	-	expression tag
Ser 104	-	expression tag
Gly 105	-	expression tag
Leu 106	-	expression tag
Val 107	-	expression tag
Pro 108	-	expression tag
Arg 109	-	expression tag
Gly 110	-	expression tag
Ser 111	-	expression tag
His 112	-	expression tag
Met 113	-	expression tag
Leu 114	-	expression tag
Glu 115	-	expression tag
Asp 116	-	expression tag
Pro 117	-	expression tag
His 118	-	expression tag
Met 119	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	62838.5
Non-Polymers*	Number of molecules	1
	Total formula weight	23.0
All*	Total formula weight	62861.5

*Water molecules are not included.