4YVP

Crystal Structure of AKR1C1 complexed with glibenclamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Aldo-keto reductase family 1 member C1	polymer	323	36839.3	2	UniProt (Q04828) Pfam (PF00248) In PDB	Homo sapiens (Human)	20-alpha-hydroxysteroid dehydrogenase,20-alpha-HSD,Chlordecone reductase homolog HAKRC,Dihydrodiol dehydrogenase 1/2,DD1/DD2,High-affinity hepatic bile acid-binding protein,HBAB,Indanol dehydrogenase,Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
2	A, B	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	2	Chemie (NAP)
3	A, B	5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide	non-polymer		494.0	2	Chemie (GBM)
4		water	water		18.0	136	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73678.7
Non-Polymers*	Number of molecules	4
	Total formula weight	2474.8
All*	Total formula weight	76153.5

*Water molecules are not included.