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4YQ6

Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
tRNA (guanine-N(1)-)-methyltransferasepolymer25428384.61UniProt (P43912)
Pfam (PF01746)
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)M1G-methyltransferase,tRNA [GM37] methyltransferase
2B
(A)
6-[(2-methoxybenzyl)amino]pyridine-3-carboxamidenon-polymer257.31Chemie (4FX)
3C
(A)
waterwater18.0153Chemie (HOH)
Sequence modifications
A: 1 - 246 (UniProt: P43912)
PDBExternal DatabaseDetails
Gly -7-expression tag
Leu -6-expression tag
Val -5-expression tag
Pro -4-expression tag
Arg -3-expression tag
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28384.6
Non-Polymers*Number of molecules1
Total formula weight257.3
All*Total formula weight28641.9
*Water molecules are not included.

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PDB entries from 2024-10-30

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