4YQ5
Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | tRNA (guanine-N(1)-)-methyltransferase | polymer | 254 | 28384.6 | 1 | UniProt (P43912) Pfam (PF01746) In PDB | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) | M1G-methyltransferase,tRNA [GM37] methyltransferase |
| 2 | A | 6-{[3-(dimethylamino)benzyl]amino}pyridine-3-carboxamide | non-polymer | 270.3 | 1 | Chemie (4G0) | |||
| 3 | A | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
| 4 | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence modifications
A: 1 - 246 (UniProt: P43912)
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28384.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 459.4 | |
| All* | Total formula weight | 28844.0 |
