4YOM

Structure of SAD kinase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	Serine/threonine-protein kinase BRSK2	polymer	350	40171.5	1	UniProt (Q69Z98) Pfam (PF00069) Pfam (PF21115)	Mus musculus (Mouse)	SADa,Serine/threonine-protein kinase SAD-A
2	B (A)	Serine/threonine-protein kinase BRSK2	polymer	144	16215.5	1	UniProt (Q69Z98) Pfam (PF21122)	Mus musculus (Mouse)	SADa,Serine/threonine-protein kinase SAD-A
3	C, D (B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4	E, F (B, A)	water	water		18.0	67	Chemie (HOH)

Sequence modifications

B: 1 - 342 (UniProt: Q69Z98)

PDB	External Database	Details
Leu 343	-	expression tag
Glu 344	-	expression tag
His 345	-	expression tag
His 346	-	expression tag
His 347	-	expression tag
His 348	-	expression tag
His 349	-	expression tag
His 350	-	expression tag

A: 519 - 653 (UniProt: Q69Z98)

PDB	External Database	Details
Met 518	-	expression tag
Leu 654	-	expression tag
Glu 655	-	expression tag
His 656	-	expression tag
His 657	-	expression tag
His 658	-	expression tag
His 659	-	expression tag
His 660	-	expression tag
His 661	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56387.0
Non-Polymers*	Number of molecules	2
	Total formula weight	124.1
All*	Total formula weight	56511.1

*Water molecules are not included.