4YNB
Crystal structure of Helicobacter pylori 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with pyrazinylthio-DADMe-Immucillin-A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Aminodeoxyfutalosine nucleosidase | polymer | 245 | 26886.9 | 1 | UniProt (Q9ZMY2) Pfam (PF01048) In PDB | Helicobacter pylori | Aminofutalosine nucleosidase,5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase,MTAN,6-amino-6-deoxyfutalosine N-ribosylhydrolase |
2 | A | (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(pyrazin-2-ylsulfanyl)methyl]pyrrolidin-3-ol | non-polymer | 357.4 | 1 | Chemie (4EH) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
4 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
5 | water | water | 18.0 | 194 | Chemie (HOH) |
Sequence modifications
A: 3 - 231 (UniProt: Q9ZMY2)
PDB | External Database | Details |
---|---|---|
Met -13 | - | initiating methionine |
Gly -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
Glu -5 | - | expression tag |
Asn -4 | - | expression tag |
Leu -3 | - | expression tag |
Tyr -2 | - | expression tag |
Phe -1 | - | expression tag |
Gln 0 | - | expression tag |
Gly 1 | - | expression tag |
Val 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 26886.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 647.7 | |
All* | Total formula weight | 27534.6 |