4YMI

Crystal structure of probable nicotinate-nucleotide adenylyltransferase from Mycobacterium abcessus in complex with NADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Probable nicotinate-nucleotide adenylyltransferase	polymer	233	25501.7	2	UniProt (B1MMZ4) Pfam (PF01467)	Mycobacterium abscessus	Deamido-NAD(+) diphosphorylase,Deamido-NAD(+) pyrophosphorylase,Nicotinate mononucleotide adenylyltransferase
2	C, F (A, B)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	2	Chemie (NAP)
3	D, E (A)	ADENINE	non-polymer		135.1	2	Chemie (ADE)
4	G, H (A, B)	water	water		18.0	305	Chemie (HOH)

Sequence modifications

A, B: 3 - 212 (UniProt: B1MMZ4)

PDB	External Database	Details
Met -20	-	initiating methionine
Ala -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Met -12	-	expression tag
Gly -11	-	expression tag
Thr -10	-	expression tag
Leu -9	-	expression tag
Glu -8	-	expression tag
Ala -7	-	expression tag
Gln -6	-	expression tag
Thr -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Met 1	-	expression tag
Val 2	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	51003.4
Non-Polymers*	Number of molecules	4
	Total formula weight	1757.1
All*	Total formula weight	52760.5

*Water molecules are not included.