4YL3
Crystal Structures of mPGES-1 Inhibitor Complexes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Prostaglandin E synthase | polymer | 148 | 16685.8 | 1 | UniProt (O14684) Pfam (PF01124) | Homo sapiens (Human) | Microsomal glutathione S-transferase 1-like 1,MGST1-L1,Microsomal prostaglandin E synthase 1,MPGES-1,p53-induced gene 12 protein |
| 2 | B (A) | 5-[4-bromo-2-(2-chloro-6-fluorophenyl)-1H-imidazol-5-yl]-2-{[4-(trifluoromethyl)phenyl]ethynyl}pyridine | non-polymer | 520.7 | 1 | Chemie (4U9) | |||
| 3 | C (A) | GLUTATHIONE | non-polymer | 307.3 | 1 | Chemie (GSH) | |||
| 4 | D, E (A) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 2 | Chemie (BOG) | |||
| 5 | F (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 6 | G (A) | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16685.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1607.0 | |
| All* | Total formula weight | 18292.8 |
