4YJR
SYK kinase domain in complex with inhibitor GTC000225
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tyrosine-protein kinase SYK | polymer | 281 | 32810.6 | 1 | UniProt (P43405) Pfam (PF07714) In PDB | Homo sapiens (Human) | Spleen tyrosine kinase,p72-Syk |
| 2 | A | 3-(1H-indazol-4-yl{2-[(1-methyl-1H-indazol-5-yl)amino]pyrimidin-4-yl}amino)propan-1-ol | non-polymer | 414.5 | 1 | Chemie (4DJ) | |||
| 3 | water | water | 18.0 | 347 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32810.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 414.5 | |
| All* | Total formula weight | 33225.1 |
