4YJP
THE KINASE DOMAIN OF HUMAN SPLEEN TYROSINE (SYK) IN COMPLEX WITH GTC000223
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase SYK | polymer | 281 | 32650.7 | 1 | UniProt (P43405) Pfam (PF07714) | Homo sapiens (Human) | Spleen tyrosine kinase,p72-Syk |
| 2 | B (A) | 2-[{2-[(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)amino]pyrimidin-4-yl}(1H-indazol-4-yl)amino]ethanol | non-polymer | 437.5 | 1 | Chemie (4DL) | |||
| 3 | C (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | D (A) | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32650.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 515.6 | |
| All* | Total formula weight | 33166.3 |
