4YJ4
Crystal structure of Bcl-xL in complex with the BIM BH3 domain containing Ile155-to-Arg and Glu158-to-phosphoserine mutations
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bcl-2-like protein 1 | polymer | 198 | 22265.3 | 1 | UniProt (Q64373) Pfam (PF02180) Pfam (PF00452) | Mus musculus (Mouse) | Bcl2-L-1,Apoptosis regulator Bcl-X |
| 2 | B (B) | Bcl-2-like protein 1, BIM BH3 domain | polymer | 21 | 2740.9 | 1 | Pfam (PF08945) UniProt (by SIFTS) (O43521) | Homo sapiens | |
| 3 | C (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | D, E (B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A: 1 - 196 (UniProt: Q64373)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
| Glu 83 | Met 83 | engineered mutation |
| Ser 84 | Ala 84 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25006.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 129.9 | |
| All* | Total formula weight | 25136.2 |
