4YH6

Crystal structure of IL1RAPL1 ectodomain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Interleukin-1 receptor accessory protein-like 1	polymer	348	39816.3	2	UniProt (P59823) Pfam (PF18452) Pfam (PF00047)	Mus musculus (Mouse)	IL1RAPL-1,X-linked interleukin-1 receptor accessory protein-like 1
2	C, F (C, F)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
3	D, E, G (D, E, G)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	3	In PDB GlyTouCan (G22768VO)
4	H (H)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
5	I (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

A, B: 19 - 352 (UniProt: P59823)

PDB	External Database	Details
Ala 12	-	expression tag
Gln 13	-	expression tag
Pro 14	-	expression tag
Ala 15	-	expression tag
Ala 16	-	expression tag
Arg 17	-	expression tag
Asp 18	-	expression tag
Lys 353	-	expression tag
His 354	-	expression tag
His 355	-	expression tag
His 356	-	expression tag
His 357	-	expression tag
His 358	-	expression tag
His 359	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79632.6
Branched	Number of molecules	6
	Total formula weight	4654.2
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	84508.0

*Water molecules are not included.