4YFI
TNNI3K complexed with inhibitor 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Serine/threonine-protein kinase TNNI3K | polymer | 330 | 37268.0 | 4 | UniProt (Q59H18) Pfam (PF07714) | Homo sapiens (Human) | Cardiac ankyrin repeat kinase,Cardiac troponin I-interacting kinase,TNNI3-interacting kinase |
| 2 | E, F, G, H (A, B, C, D) | N-methyl-3-(9H-purin-6-ylamino)benzenesulfonamide | non-polymer | 304.3 | 4 | Chemie (4CW) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 402 - 730 (UniProt: Q59H18)
| PDB | External Database | Details |
|---|---|---|
| Gly 401 | - | expression tag |
| Asp 674 | Ala 775 | conflict |
| Met 675 | Ala 776 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 149071.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1217.3 | |
| All* | Total formula weight | 150289.2 |
