4YDO

CRYSTAL STRUCTURE OF CANDIDA ALBICANS PROTEIN FARNESYLTRANSFERASE IN APO FORM

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	polymer	329	39236.8	1	UniProt (Q9Y765)	Candida albicans (Yeast)	CAAX farnesyltransferase subunit alpha,FTase-alpha,Ras proteins prenyltransferase subunit alpha,Type I protein geranyl-geranyltransferase subunit alpha,GGTase-I-alpha
2	B (B)	Uncharacterized protein	polymer	587	66693.3	1	UniProt (Q59LE1)	Candida albicans (Yeast)
3	C, E (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	D (B)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
5	F, G (A, B)	water	water		18.0	44	Chemie (HOH)

Sequence modifications

A: 1 - 305 (UniProt: Q9Y765)

PDB	External Database	Details
Met -23	-	initiating methionine
Gly -22	-	expression tag
Ser -21	-	expression tag
Ser -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
Ser -13	-	expression tag
Gln -12	-	expression tag
Asp -11	-	expression tag
Pro -10	-	expression tag
Asn -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Ser -6	-	expression tag
Ala -5	-	expression tag
Arg -4	-	expression tag
Leu -3	-	expression tag
Gln -2	-	expression tag
Val -1	-	expression tag
Asp 0	-	expression tag
Ile 38	Leu 38	conflict
Ser 41	Ala 41	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	105930.1
Non-Polymers*	Number of molecules	3
	Total formula weight	145.6
All*	Total formula weight	106075.6

*Water molecules are not included.