4YDN
High resolution crystal structure of human transthyretin bound to ligand and conjugates of 4-(5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl)phenyl fluorosulfate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transthyretin | polymer | 127 | 13856.4 | 2 | UniProt (P02766) Pfam (PF00576) | Homo sapiens (Human) | ATTR,Prealbumin,TBPA |
| 2 | C, E (A, B) | 4-[5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]phenyl sulfurofluoridate | non-polymer | 405.2 | 2 | Chemie (2WN) | |||
| 3 | D (A) | 2,6-dichloro-4-[5-(4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]phenol | non-polymer | 323.1 | 1 | Chemie (4B8) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27712.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1133.5 | |
| All* | Total formula weight | 28846.3 |
