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4YDN

High resolution crystal structure of human transthyretin bound to ligand and conjugates of 4-(5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl)phenyl fluorosulfate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BTransthyretinpolymer12713856.42UniProt (P02766)
Pfam (PF00576)
In PDB
Homo sapiens (Human)ATTR,Prealbumin,TBPA
2A, B4-[5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]phenyl sulfurofluoridatenon-polymer405.22Chemie (2WN)
3A2,6-dichloro-4-[5-(4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]phenolnon-polymer323.11Chemie (4B8)
4waterwater18.0156Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27712.8
Non-Polymers*Number of molecules3
Total formula weight1133.5
All*Total formula weight28846.3
*Water molecules are not included.

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PDB entries from 2024-06-12

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