4YD0
Influenza polymerase basic protein 2 (PB2) bound to an azaindole-tetrazole inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Polymerase basic protein 2 | polymer | 169 | 19174.3 | 1 | UniProt (Q30NP1) Pfam (PF00604) | Influenza A virus | RNA-directed RNA polymerase subunit P3 |
| 2 | B (A) | 2-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoro-N-[(1R,2S,3S,4R)-3-(1H-tetrazol-5-yl)bicyclo[2.2.2]oct-2-yl]pyrimidin-4-amine | non-polymer | 439.9 | 1 | Chemie (4EW) | |||
| 3 | C (A) | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A: 18 - 183 (UniProt: Q30NP1)
| PDB | External Database | Details |
|---|---|---|
| Gly 15 | - | expression tag |
| His 16 | - | expression tag |
| Met 17 | - | expression tag |
| Lys 89 | Arg 389 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19174.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 439.9 | |
| All* | Total formula weight | 19614.2 |
