4YBU
Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y mutant of human Cellular Retinoic Acid Binding ProteinII in complex with Retinal after 24 h incubation and 1 hour UV irradiation at 1.92 angstrom - 1st cycle
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cellular retinoic acid-binding protein 2 | polymer | 137 | 15543.7 | 1 | UniProt (P29373) Pfam (PF00061) | Homo sapiens (Human) | Cellular retinoic acid-binding protein II,CRABP-II |
| 2 | B (A) | RETINAL | non-polymer | 284.4 | 1 | Chemie (RET) PubChem (1070) PubChem (23254473) PubChem (177675058) PubChem (638015) PubChem (5353924) PubChem (6436079) PubChem (6436082) PubChem (87082476) PubChem (87110449) PubChem (87110609) PubChem (88398773) PubChem (88407543) PubChem (11426127) PubChem (12227253) PubChem (12227254) PubChem (12227256) PubChem (12227257) PubChem (12227258) PubChem (12227259) PubChem (12227269) PubChem (12227270) PubChem (12227271) PubChem (5280490) PubChem (5381765) PubChem (134688327) PubChem (140510408) PubChem (145826762) PubChem (169423542) PubChem (172878320) | |||
| 3 | C (A) | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A: 1 - 137 (UniProt: P29373)
| PDB | External Database | Details |
|---|---|---|
| Gln 39 | Pro 40 | engineered mutation |
| Val 54 | Thr 55 | engineered mutation |
| Tyr 59 | Arg 60 | engineered mutation |
| Lys 111 | Arg 112 | engineered mutation |
| Gln 132 | Arg 133 | engineered mutation |
| Phe 134 | Tyr 135 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15543.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 284.4 | |
| All* | Total formula weight | 15828.2 |
