4YAB
Crystal structure of TRIM24 PHD-bromodomain complexed with 1-methyl-5-(2-methyl-1 3-thiazol-4-yl)-2 3-dihydro-1H-indol-2-one (1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transcription intermediary factor 1-alpha | polymer | 184 | 21318.4 | 2 | UniProt (O15164) Pfam (PF00628) Pfam (PF00439) | Homo sapiens (Human) | TIF1-alpha,E3 ubiquitin-protein ligase TRIM24,RING finger protein 82,Tripartite motif-containing protein 24 |
| 2 | C, D, G, H (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, I (A, B) | 1-methyl-5-(2-methyl-1,3-thiazol-4-yl)-1,3-dihydro-2H-indol-2-one | non-polymer | 244.3 | 2 | Chemie (4CN) | |||
| 4 | F, J (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 404 | Chemie (HOH) |
Sequence modifications
A, B: 824 - 1006 (UniProt: O15164)
| PDB | External Database | Details |
|---|---|---|
| Ser 823 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42636.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 942.4 | |
| All* | Total formula weight | 43579.2 |
