4Y8C

Crystal structure of phosphodiesterase 9 in complex with (S)-C33

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	polymer	533	61789.1	2	UniProt (O76083) Pfam (PF00233)	Homo sapiens (Human)
2	C, F (A, B)	6-{[(1S)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one	non-polymer		357.8	2	Chemie (49D)
3	D, G (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	E, H (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	I, J (A, B)	water	water		18.0	12	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	123578.2
Non-Polymers*	Number of molecules	6
	Total formula weight	895.1
All*	Total formula weight	124473.3

*Water molecules are not included.