4Y5S

Structure of FtmOx1 with a-Ketoglutarate as co-substrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Verruculogen synthase	polymer	315	35381.3	2	UniProt (Q4WAW9) Pfam (PF05721)	Neosartorya fumigata	Fumitremorgin biosynthesis protein F
2	C, E (A, B)	2-OXOGLUTARIC ACID	non-polymer		146.1	2	Chemie (AKG)
3	D, F (A, B)	FE (II) ION	non-polymer		55.8	2	Chemie (FE2)
4	G (B)	COBALT (II) ION	non-polymer		58.9	1	Chemie (CO)
5	H, I (A, B)	water	water		18.0	146	Chemie (HOH)

Sequence modifications

A, B: 6 - 295 (UniProt: Q4WAW9)

PDB	External Database	Details
Gly 2	-	expression tag
Pro 3	-	expression tag
Glu 4	-	expression tag
Phe 5	-	expression tag
Leu 296	-	expression tag
Glu 297	-	expression tag
Val 298	-	expression tag
Asp 299	-	expression tag
Leu 300	-	expression tag
Gln 301	-	expression tag
Gly 302	-	expression tag
Asp 303	-	expression tag
His 304	-	expression tag
Gly 305	-	expression tag
Leu 306	-	expression tag
Ser 307	-	expression tag
Ala 308	-	expression tag
Trp 309	-	expression tag
Ser 310	-	expression tag
His 311	-	expression tag
Pro 312	-	expression tag
Gln 313	-	expression tag
Phe 314	-	expression tag
Glu 315	-	expression tag
Lys 316	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	70762.6
Non-Polymers*	Number of molecules	5
	Total formula weight	462.8
All*	Total formula weight	71225.4

*Water molecules are not included.