4Y1C
Cyclic hexapeptide cyc[NdPopPKID] in complex with HIV-1 integrase core domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Integrase | polymer | 167 | 18215.6 | 2 | UniProt (Q76353) Pfam (PF00665) UniProt (by SIFTS) (P12497) | Human immunodeficiency virus 1 | |
| 2 | C (C) | Cyclic hexapeptide cyc[NdPopPKID] | polymer | 6 | 737.8 | 1 | synthetic construct | ||
| 3 | D, E, G, H (A, B) | CADMIUM ION | non-polymer | 112.4 | 4 | Chemie (CD) | |||
| 4 | F, I (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A, B: 50 - 212 (UniProt: Q76353)
| PDB | External Database | Details |
|---|---|---|
| Met 46 | - | initiating methionine |
| Gly 47 | - | expression tag |
| Ser 48 | - | expression tag |
| His 49 | - | expression tag |
| Ser 56 | Cys 56 | engineered mutation |
| Asp 131 | Trp 131 | engineered mutation |
| Asp 139 | Phe 139 | engineered mutation |
| His 185 | Phe 185 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 37169.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 641.8 | |
| All* | Total formula weight | 37810.9 |
