4Y16
Crystal structure of the mCD1d/NC-aGC/iNKTCR ternary complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Antigen-presenting glycoprotein CD1d1 | polymer | 285 | 32632.7 | 1 | UniProt (P11609) Pfam (PF16497) Pfam (PF07654) | Mus musculus (Mouse) | |
| 2 | B (B) | Beta-2-microglobulin | polymer | 99 | 11660.4 | 1 | UniProt (P01887) Pfam (PF07654) | Mus musculus (Mouse) | |
| 3 | C (C) | Chimeric TCR Valpha14/Jalpha18 chain (mouse variable domain, human constant domain) | polymer | 209 | 23055.6 | 1 | Pfam (PF07686) Pfam (PF09291) UniProt (by SIFTS) (A0A0B4J1J9) UniProt (by SIFTS) (P01848) | Mus musculus Homo sapiens (Mouse Human) | Protein Trav11d,Human nkt tcr beta chain |
| 4 | D (D) | Chimeric TCR Vbeta8.2 chain (mouse variable domain, human constant domain) | polymer | 241 | 27027.0 | 1 | Pfam (PF07686) Pfam (PF07654) UniProt (by SIFTS) (A2NTY6) UniProt (by SIFTS) (A0A5B9) | Mus musculus Homo sapiens (Mouse Human) | Beta-chain,T-cell receptor beta-2 chain C region |
| 5 | E (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 6 | F (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G28454KX) | |||
| 7 | G (A) | N-[(2S,3S,4R)-3,4-dihydroxy-1-{[6-O-(naphthalen-1-ylcarbamoyl)-alpha-D-galactopyranosyl]oxy}octadecan-2-yl]hexacosanamide | non-polymer | 1027.5 | 1 | Chemie (48G) | |||
| 8 | H (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 9 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A: 1 - 279 (UniProt: P11609)
| PDB | External Database | Details |
|---|---|---|
| His 201 | Asp 219 | variant |
| His 280 | - | expression tag |
| His 281 | - | expression tag |
| His 282 | - | expression tag |
| His 283 | - | expression tag |
| His 284 | - | expression tag |
| His 285 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 94375.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 994.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1248.7 | |
| All* | Total formula weight | 96619.3 |
