4Y10
Trypsin in complex with with BPTI mutant (2S)-2-amino-4,4-difluorobutanoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | E | Cationic trypsin | polymer | 223 | 23324.3 | 1 | UniProt (P00760) Pfam (PF00089) In PDB | Bos taurus (Cattle) | Beta-trypsin, trypsin |
| 2 | I | Pancreatic trypsin inhibitor | polymer | 58 | 6519.5 | 1 | UniProt (P00974) Pfam (PF00014) In PDB | Bos taurus | Aprotinin,Basic protease inhibitor,BPTI |
| 3 | E, I | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
| 4 | E | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | water | water | 18.0 | 346 | Chemie (HOH) |
Sequence modifications
I: 1 - 58 (UniProt: P00974)
| PDB | External Database | Details |
|---|---|---|
| Obf 15 | Lys 50 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29843.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 996.7 | |
| All* | Total formula weight | 30840.5 |
